We currently have ciphers optimized for performance, for
compatibility, for size and for specific CPUs.
However we lack a class of ciphers that is becoming increasingly
important, as Zig is being used for embedded systems, but also as
hardware-level side channels keep being found on (Intel) CPUs.
Here is ISAPv2, a construction specifically designed for resilience
against leakage and fault attacks.
ISAPv2 is obviously not optimized for performance, but can be an
option for highly sensitive data, when the runtime environment cannot
be trusted.
Andrew Kelley
Frank Denis